Fate's Little Feral Consort - Chapter 1510

Meet Sora and Shiro, a brother and sister who are loser shut-ins by normal standards. But these siblings don’t play by the rules of the “crappy game” that is average society. In the world of gaming, this genius pair reigns supreme, their invincible avatar so famous that it’s the stuff of urban legend. So when a young boy calling himself God summons the siblings to a fantastic alternate world where war is forbidden and all conflicts–even those involving national borders–are decided by the outcome of games, Sora and Shiro have pretty much hit the jackpot. But they soon learn that in this world, humanity, cornered and outnumbered by other species, survives within the confines of one city. Will Sora and Shiro, two failures at life, turn out to be the saviors of mankind? Let the games begin…

A skilled but unfortunate modern-day assassin was killed in a freak accident. However, he soon found himself summoned to another world by an evil wizard, who had him possess the body of a boy as an experiment. After successfully planning the evil wizard’s downfall, he used the wizard’s body as a springboard to gain influence and power in his new world.

- Description from Novelupdates

I’ve reincarnated as the reverse harem game’s villainess, the one and only step-daughter of the Eckart duke family.